
In last season's cliff-hanger, Izzie underwent successful brain surgery but lost her short-term memory, flat-lining during the last minutes of the finale.

"Grey's Anatomy" debuted on ABC as a mid-season replacement for "Boston Legal", March 27, 2005, revolving around surgical interns 'Dr. Meredith Grey' (Ellen Pompeo), and Izzy Stevens at 'Seattle Grace Hospital' in Seattle, Washington.
April 23, 2009, ABC picked up "Grey's Anatomy" for the 2009–2010 television season, with the first episode of the sixth season airing Thursday, September 24, 2009...