Directed by Phyllida Lloyd, the film co-stars Jim Broadbent as 'Denis Thatcher' and Anthony Head as cabinet minister 'Geoffrey Howe.
"The prospect of exploring the swathe cut through history by this remarkable woman is a daunting and exciting challenge," said Streep.
"I am trying to approach the role with as much zeal, fervour and attention to detail as the real 'Lady Thatcher' possesses – I can only hope my stamina will begin to approach her own..."
The film is narrated through a series of flashbacks, including the 17 days leading up to the Falklands War in 1982.
"The Iron Lady" is a Pathé, Film4, UK Film Council presentation with the participation of Canal+ and Cine Cinema in association with Goldcrest Film Production LLP of a DJ Films Production.
Click the images to enlarge and Sneak Peek "The Iron Lady"...
Click the images to enlarge and Sneak Peek "The Iron Lady"...