
"..'Yorick Brown' and 'Agent 355' prepare for their ultimate quest to reunite the last man with his lost love, while the person, people or thing behind the disaster that wiped out half of humanity is revealed. Then, Yorick's long journey through an Earth populated only by women comes to its dramatic, unexpected conclusion..."
The series was published in sixty issues by Vertigo and collected in a series of ten paperback volumes, with covers primarily by J. G. Jones and Carnevale.
"July 17, 2002, a plague simultaneously kills every living mammal possessing a Y chromosome — including embryos, fertilized eggs and sperm. The only exceptions appear to be New York residents 'Yorick Brown', a young amateur escape artist and his male Capuchin monkey, 'Ampersand'.

"Society is plunged into chaos as infrastructures collapse and the surviving women everywhere try to cope with the loss of the men, their survivor guilt, and the knowledge that - barring a rapid, major scientific breakthrough or other extraordinary happening - humanity is doomed to extinction.
Film rights to the series were acquired by New Line Cinema with director Louis Letterier currently expressing an interest to adapt the comic books into a TV series.
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